Over the years, there have been many changes to the medications designed to treat migraines. This treatment cannot stop migraine attacks, but it can reduce pain and other symptoms.
There are a number of treatments for migraine, ranging from preventive medicine, over-the-counter medications, prescription medications, and alternative therapies.
Ergotamine is an alpha adrenergic blocking agent with a direct stimulating effect on the smooth muscle of peripheral and cranial blood vessels and produces depression of central vasomotor centers.
Migraine headaches are severe, throbbing, paroxysmal and often located on one side of the skull, near the eye socket or temple, and less often in the occiput.
CAFERGOT (ergotamine tartrate and caffeine tablets, USP) are indicated as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so-called "histaminic cephalalgia."
Each Cafergot tablet contains 1 mg of ergotamine tartrate and 100 mg of caffeine.
Antimigraine, Corrective Metabolism Of Bone And Cartilaginous Tissue
Combined preparation Cafergot for relieving migraine attacks, as well as relief of severe headache attacks of vascular origin.
Severe arterial hypertension, hepatic or renal failure, pregnancy, lactation.
Cafergot should be taken at the very beginning of an attack. For the first dose, a dose of 2 tablets is recommended.
If symptoms such as numbness of the fingertips or feet appear, the drug should be stopped immediately and a doctor should be consulted.
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Take this medication by mouth with or without food as directed by your doctor.
Cafergot is a combined drug that relieves migraine attacks and headaches of vascular genesis. Ergotamine normalizes the tone of the enlarged extracranial arteries. Caffeine accelerates and increases the absorption of ergotamine in the intestine.
Indications for the use of Cafergot are: acute migraine attacks and similar attacks of headaches of vascular genesis.
Cafergot may be taken with or without food.
Eating grapefruit or drinking grapefruit juice may affect the amount of Cafergot in your blood. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
Cafergot is only to be used as needed for a migraine attack.
Take Cafergot at the first sign of a headache. If the initial dose does not relieve your headache, additional doses may be needed according to your doctor's instructions. Do not take a dose of Cafergot within 30 minutes of your last dose.
Do not take more than 6 tablets for a single migraine headache or more than 10 tablets during any 7-day period without first checking with your doctor.
If you miss a dose of Cafergot and you still have a headache, take it as soon as you remember. Do not take a dose of Cafergot within 30 minutes of your last dose. Do not take 2 doses at once.
Cafergot (ergotamine tartrate and caffeine tablets, USP) should not be administered with other vasoconstrictors. Use with sympathomimetics (pressor agents) may cause extreme elevation of blood pressure. The beta-blocker Inderal (propranolol) has been reported to potentiate the vasoconstrictive action of Cafergot (ergotamine tartrate and caffeine tablets, USP) by blocking the vasodilating property of epinephrine. Nicotine may provoke vasoconstriction in some patients, predisposing to a greater ischemic response to ergot therapy.
The blood levels of ergotamine-containing drugs are reported to be elevated by the concomitant administration of macrolide antibiotics and vasospastic reactions have been reported with therapeutic doses of the ergotamine-containing drugs when coadministered with these antibiotics.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Nausea.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue color of the fingers or toes; chest pain or tightness; cold or pale fingers or toes; diarrhea; dizziness; hallucinations; headache; irregular heartbeat; leg cramps or weakness; mental or mood changes; muscle pain; numbness or tingling of the hands, feet, or skin; ringing in the ears; seizure; severe or persistent nausea or vomiting; shortness of breath; swelling; temporary fast or slow heartbeat; vomiting; weak pulse.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.
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Migraine is a neurological condition typically characterized by headaches that are often so excruciating and debilitating that they interfere with your ability to accomplish anything and make it hard just to get through the day.
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